Michael Schoppet Selected Research

Osteoprotegerin

1/2013	TRAIL-deficiency accelerates vascular calcification in atherosclerosis via modulation of RANKL.
2/2012	Osteoprotegerin (OPG) and TNF-related apoptosis-inducing ligand (TRAIL) levels in malignant and benign pericardial effusions.
8/2011	Calcium and osteoprotegerin regulate IGF1R expression to inhibit vascular calcification.
9/2009	Osteoprotegerin production by breast cancer cells is suppressed by dexamethasone and confers resistance against TRAIL-induced apoptosis.
8/2009	Inhibition of receptor activator of NF-kappaB ligand by denosumab attenuates vascular calcium deposition in mice.
4/2008	17beta-Estradiol inhibits osteoprotegerin production by the estrogen receptor-alpha-positive human breast cancer cell line MCF-7.
4/2006	Interleukin-4 differentially regulates osteoprotegerin expression and induces calcification in vascular smooth muscle cells.
2/2006	Osteoprotegerin (OPG) and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) levels in atherosclerosis.
12/2005	TNF-related apoptosis-inducing ligand and its decoy receptor osteoprotegerin in nonischemic dilated cardiomyopathy.
8/2004	Localization of osteoprotegerin, tumor necrosis factor-related apoptosis-inducing ligand, and receptor activator of nuclear factor-kappaB ligand in Mönckeberg's sclerosis and atherosclerosis.

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Michael Schoppet Research Topics

Disease

8	Vascular Calcification 03/2017 - 08/2004
5	Vascular Diseases (Vascular Disease) 10/2015 - 09/2002
5	Bone Resorption 08/2009 - 07/2004
5	Osteoporosis 08/2009 - 04/2002
4	Atherosclerotic Plaque (Atheroma) 07/2013 - 04/2011
4	Breast Neoplasms (Breast Cancer) 01/2010 - 11/2005
4	Neoplasms (Cancer) 01/2010 - 07/2004
4	Atherosclerosis 11/2008 - 08/2004
4	Coronary Artery Disease (Coronary Atherosclerosis) 12/2005 - 03/2003
2	Pericardial Effusion 02/2012 - 05/2005
2	Neoplasm Metastasis (Metastasis) 01/2010 - 07/2004
2	Infections 03/2008 - 07/2003
2	Postmenopausal Osteoporosis 11/2005 - 07/2004
1	Hypertension (High Blood Pressure) 10/2015
1	Diabetes Mellitus 12/2011
1	Autoimmune Diseases (Autoimmune Disease) 03/2008
1	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 12/2005
1	Neointima 08/2004
1	Monckeberg Medial Calcific Sclerosis 08/2004
1	Bone Diseases (Bone Disease) 07/2004
1	Rheumatoid Arthritis 07/2004
1	Disease Progression 09/2003
1	Sarcoidosis (Schaumann Disease) 09/2003
1	Myocarditis (Carditis) 01/2003
1	Hyperostosis corticalis deformans juvenilis 11/2002
1	Osteopetrosis 04/2002
1	Thyroid Diseases (Thyroid Disease) 01/2002
1	Graves Disease (Basedow Disease) 01/2002

Drug/Important Bio-Agent (IBA)

15	OsteoprotegerinIBA 01/2013 - 09/2002
8	CytokinesIBA 01/2013 - 01/2002
6	Proteins (Proteins, Gene)FDA Link 03/2017 - 09/2003
6	Messenger RNA (mRNA)IBA 01/2013 - 01/2002
4	CalciumIBA 10/2015 - 08/2009
4	LigandsIBA 01/2013 - 08/2004
4	TNF-Related Apoptosis-Inducing LigandIBA 01/2013 - 08/2004
3	GlucocorticoidsIBA 08/2009 - 07/2004
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 03/2008 - 08/2004
2	Apolipoproteins E (ApoE)IBA 07/2013 - 01/2013
2	Estrogen ReceptorsIBA 01/2010 - 04/2008
2	deoxypyridinolineIBA 08/2009 - 05/2009
2	Denosumab FDA Link 08/2009 - 05/2009
2	Estrogens (Estrogen)FDA Link 04/2008 - 07/2004
2	RANK LigandIBA 08/2004 - 03/2003
1	Prothrombin (Factor II)IBA 03/2017
1	AnticoagulantsIBA 03/2017
1	Pharmaceutical PreparationsIBA 03/2017
1	Blood Coagulation Factors (Coagulation Factor)IBA 03/2017
1	Vitamin K FDA Link 03/2017
1	Warfarin (Coumadin)FDA LinkGeneric 03/2017
1	Biomarkers (Surrogate Marker)IBA 10/2015
1	Fibroblast Growth Factor-23IBA 10/2015
1	Phosphates (Orthophosphate)IBA 10/2015
1	alpha-2-HS-GlycoproteinIBA 10/2015
1	CollagenIBA 01/2013
1	LipidsIBA 08/2012
1	MineralsIBA 08/2012
1	Sodium Hydroxide (Caustic Soda)FDA Link 08/2012
1	Sodium Hypochlorite (Clorox)IBA 08/2012
1	oxidized low density lipoproteinIBA 12/2011
1	Annexin A6IBA 04/2011
1	Carrier Proteins (Binding Protein)IBA 04/2011
1	Phospholipids (Phosphatides)FDA LinkGeneric 04/2011
1	Zoledronic Acid (Zometa)FDA Link 01/2010
1	Diphosphonates (Bisphosphonates)IBA 01/2010
1	Dexamethasone (Maxidex)FDA LinkGeneric 09/2009
1	Monoclonal AntibodiesIBA 05/2009
1	Tartrate-Resistant Acid PhosphataseIBA 05/2009
1	Biological ProductsIBA 11/2008
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 04/2008
1	Estrogen Receptor alphaIBA 04/2008
1	AndrogensIBA 04/2008
1	NF-kappa B (NF-kB)IBA 03/2008
1	InterleukinsIBA 04/2006
1	Interleukin-4 (Interleukin 4)IBA 04/2006
1	Matrix Metalloproteinases (MMPs)IBA 05/2005
1	Peptide Hydrolases (Proteases)FDA Link 05/2005
1	AntibodiesIBA 07/2004
1	EnzymesIBA 09/2003
1	Interleukin-6 (Interleukin 6)IBA 09/2003
1	ImmunosorbentsIBA 09/2003
1	Immunoglobulin M (IgM)IBA 07/2003
1	AutoantigensIBA 01/2003
1	Glycoproteins (Glycoprotein)IBA 04/2002

Therapy/Procedure

2	Therapeutics 11/2005 - 07/2004
1	Estrogen Replacement Therapy 11/2005
1	Ligation 08/2004